Click here to see all the TRIP Evidence Reviews.
Evidence-Based Reports
- Epilepsy or a family history of epilepsy increases the risk of schizophrenia or schizophrenia-like psychosis. Evidence-Based Mental Health (requires free registration), 2006
- Schizophrenia and suicide. Bandolier, 2006 View article OR Can you answer this related question for extra CPD?
- Stable monotherapy with clozapine or olanzapine increases the incidence of diabetes mellitus in people with schizophrenia. Evidence-Based Mental Health (requires free registration), 2005
- Aripiprazole is effective for relapse prevention in people with chronic stable schizophrenia. Evidence-Based Mental Health (requires free registration), 2005
- NHS study questions use of new schizophrenia drugs. Hitting the Headlines, 2006
- Review: high doses of antipsychotic drugs are no more or less effective than medium doses in people with schizophrenia. Evidence-Based Mental Health (requires free registration), 2005
- About 30% of men with schizophrenia or schizoaffective disorders have obsessive-compulsive symptoms. Evidence-Based Mental Health (requires free registration), 2006
- Review: women with schizophrenia have poorer pregnancy outcomes than other women, but it is unclear whether antipsychotic medications affect their infants. Evidence-Based Mental Health (requires free registration), 2004
Clinical Guidelines
- Schizophrenia. PRODIGY, 2007
- Schizophrenia: core interventions in the treatment and management of schizophrenia in primary and secondary care. NICE, 2002
- Consensus statement on high-dose antipsychotic medication. Royal College of Psychiatrists, 2006
- Practice guideline for the treatment of patients with schizophrenia. American Psychiatric Association, 2004
- Summary Australian and New Zealand Clinical Practice Guideline for the Treatment of Schizophrenia. New Zealand Guidelines Group, 2005
Systematic Reviews
- Benzodiazepines for schizophrenia. Cochrane Database of Systematic Reviews. 2007 View article OR Can you answer this related question for extra CPD?
- Interventions to reduce weight gain in schizophrenia. Cochrane Database of Systematic Reviews, 2007
- Mother and baby units for schizophrenia. Cochrane Database of Systematic Reviews, 2007
- Molindone for schizophrenia and severe mental illness. Cochrane Database of Systematic Reviews, 2007
- Depot fluspirilene for schizophrenia. Cochrane Database of Systematic Reviews, 2007 View article OR Can you answer this related question for extra CPD?
- Cessation of medication for people with schizophrenia already stable on chlorpromazine. Cochrane Database of Systematic Reviews, 2007
- Drama therapy for schizophrenia or schizophrenia-like illnesses. Cochrane Database of Systematic Reviews, 2007
Recent articles in core journals
- Paliperidone extended-release tablets for prevention of symptom recurrence in patients with schizophrenia: a randomized, double-blind, placebo-controlled study. Journal of Clinical Psychopharmacology, 2007
- Randomized controlled trial of the effect on Quality of Life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1). Archives of General Psychiatry, 2006
- Association of schizophrenia and autoimmune diseases: linkage of Danish national registers. American Journal of Psychiatry, 2006
- Childhood-onset schizophrenia: A double-blind, randomized clozapine-olanzapine comparison. Archives of General Psychiatry, 2006
- Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment. American Journal of Psychiatry, 2006
- Long-term course of cognitive impairment in schizophrenia. British Journal of Psychiatry, 2006
- Adherence therapy for people with schizophrenia. European multicentre randomised controlled trial. British Journal of Psychiatry, 2006
- Elevated prenatal homocysteine levels as a risk factor for schizophrenia. Archives of General Psychiatry, 2007
eTextbooks
- eMedicine
- eMedicine. Schizophrenia and Other Psychoses (pediatrics)
- Merck Manual
- Merck Manual (childhood)
- GP Notebook
Clinical Queries
- I was told by a psychiatrist that Efamarine capsules are beneficial in schizophrenia when combined with antipsychotics. Is there any research evidence for this and if so what is it? NLH Q&A Service, 2006
- For a woman with a history of schizophrenia, using sodium valproate and amisulpride what contraceptive options are available? Faculty of Family Planning & Reproductive Health Care Q&A, 2006
- Is it advised to perform routine ECGs on all schizophrenic patients prior to commencing on atypical antipsychotic medication? ATTRACT, 2005
Patient Information
